Tocolytic Agents : Anti-contraction Medicine

    Tocolytic Agents

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    ➯Definition of Tocolytic Agents

    Tocolytic Agents are also called anti-contraction medications or labor suppressants. those agents prevent preterm labor and immature birth by suppressing uterine contractions.


    ➯Indications of Tocolytic Agents

    • Generally 24 gestational weeks onward.
    • Before 37 weeks of gestation.
    • Spontaneous premature contraction.
    • No evidence of infection
    • No life-threatening

    ➯Contraindications of Tocolytic Agents:

    • Fetus is older than 34 weeks gestation
    • Fetus weighs less than 2.5 kg
    • intrauterine growth restriction (IUGR)
    • placental insufficiency
    • Chromosomal abnormalities
    • Cervical dilation is greater than 4 centimetres
    • Chorioamnionitis – intrauterine infection is present
    • pregnancy-induced hypertension
    • Eclampsia
    • Preeclampsia
    • active vaginal bleeding
    • placental abruption
    • a cardiac disease
    • another condition which indicates that the pregnancy should not continue.

    ➯TOCOLYTICS(UTERINE RELAXANTS)

            It’s Not My Time!

    I – Indomethacin (NSAID)

    N – Nifedipine (CA Channel Blocker)

    M – Magnesium Sulfate

    T – Terbutaune (Adrenergic Agonist)

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